Christopher O'Connor, MD


Professor of Medicine
Chief, Division of Cardiology
Director, Duke Heart Center
Department / Division:
Medicine / Medicine - Cardiology
Address:
DUMC 3356
Durham, NC 27710
Appointment Telephone:
919-681-5816
Office Telephone:
919-681-6195
Fax:
919-681-7755
Training:
  • MD, University of Maryland School of Medicine, 1983
Residency:
  • Internal Medicine-Cardiology, Duke University Medical Center, 1983-1986, 1986-1987, 1988-1989
Clinical Interests:
Management of heart failure; chronic ischemic heart disease
Research Interests:
Dr. O’Connor’s research interests include: acute heart failure; co-morbidities in heart failure; clinical trials; biomarkers; and novel pharmacological and non-pharmacological approaches for the treatment of heart failure.
Representative Publications:
  • Felker, GM; Lee, KL; Bull, DA; Redfield, MM; Stevenson, LW; Goldsmith, SR; LeWinter, MM; Deswal, A; Rouleau, JL; Ofili, EO; Anstrom, KJ; Hernandez, AF; McNulty, SE; Velazquez, EJ; Kfoury, AG; Chen, HH; Givertz, MM; Semigran, MJ; Bart, BA; Mascette, AM; Braunwald, E; O'Connor, CM; NHLBI Heart Failure Clinical Research Network. Diuretic strategies in patients with acute decompensated heart failure. New England Journal of Medicine. 2011;364:797-805.  Abstract
  • O'Connor, CM; Starling, RC; Hernandez, AF; Armstrong, PW; Dickstein, K; Hasselblad, V; Heizer, GM; Komajda, M; Massie, BM; McMurray, JJ; Nieminen, MS; Reist, CJ; Rouleau, JL; Swedberg, K; Adams, KF; Anker, SD; Atar, D; Battler, A; Botero, R; Bohidar, NR; Butler, J; Clausell, N; Corbalán, R; Costanzo, MR; Dahlstrom, U; Deckelbaum, LI; Diaz, R; Dunlap, ME; Ezekowitz, JA; Feldman, D; Felker, GM; Fonarow, GC; Gennevois, D; Gottlieb, SS; Hill, JA; Hollander, JE; Howlett, JG; Hudson, MP; Kociol, RD; Krum, H; Laucevicius, A; Levy, WC; Méndez, GF; Metra, M; Mittal, S; Oh, BH; Pereira, NL; Ponikowski, P; Tang, WH; Tanomsup, S; Teerlink, JR; Triposkiadis, F; Troughton, RW; Voors, AA; Whellan, DJ; Zannad, F; Califf, RM. Effect of nesiritide in patients with acute decompensated heart failure. New England Journal of Medicine. 2011;365:32-43.  Abstract
  • Sherwood, A; Blumenthal, JA; Hinderliter, AL; Koch, GG; Adams, KF; Dupree, CS; Bensimhon, DR; Johnson, KS; Trivedi, R; Bowers, M; Christenson, RH; O'Connor, CM. Worsening depressive symptoms are associated with adverse clinical outcomes in patients with heart failure. Journal of the American College of Cardiology. 2011;57:418-423.  Abstract
  • O'Connor, CM; Hasselblad, V; Mehta, RH; Tasissa, G; Califf, RM; Fiuzat, M; Rogers, JG; Leier, CV; Stevenson, LW. Triage after hospitalization with advanced heart failure: the ESCAPE (Evaluation Study of Congestive Heart Failure and Pulmonary Artery Catheterization Effectiveness) risk model and discharge score. Journal of the American College of Cardiology. 2010;55:872-878.  Abstract
  • O'Connor, CM; Jiang, W; Kuchibhatla, M; Silva, SG; Cuffe, MS; Callwood, DD; Zakhary, B; Stough, WG; Arias, RM; Rivelli, SK; Krishnan, R; SADHART-CHF Investigators. Safety and efficacy of sertraline for depression in patients with heart failure: results of the SADHART-CHF (Sertraline Against Depression and Heart Disease in Chronic Heart Failure) trial. Journal of the American College of Cardiology. 2010;56:692-699.  Abstract
  • Flynn, KE; Piña, IL; Whellan, DJ; Lin, L; Blumenthal, JA; Ellis, SJ; Fine, LJ; Howlett, JG; Keteyian, SJ; Kitzman, DW; Kraus, WE; Miller, NH; Schulman, KA; Spertus, JA; O'Connor, CM; Weinfurt, KP; HF-ACTION Investigators. Effects of exercise training on health status in patients with chronic heart failure: HF-ACTION randomized controlled trial. JAMA: Journal of the American Medical Association. 2009;301:1451-1459.  Abstract
  • O'Connor, CM; Whellan, DJ; Lee, KL; Keteyian, SJ; Cooper, LS; Ellis, SJ; Leifer, ES; Kraus, WE; Kitzman, DW; Blumenthal, JA; Rendall, DS; Miller, NH; Fleg, JL; Schulman, KA; McKelvie, RS; Zannad, F; Piña, IL; HF-ACTION Investigators. Efficacy and safety of exercise training in patients with chronic heart failure: HF-ACTION randomized controlled trial. JAMA: Journal of the American Medical Association. 2009;301:1439-1450.  Abstract
  • O'Connor, CM; Califf, RM; Massey, EW; Mark, DB; Kereiakes, DJ; Candela, RJ; Abbottsmith, C; George, B; Stack, RS; Aronson, L. Stroke and acute myocardial infarction in the thrombolytic era: clinical correlates and long-term prognosis. Journal of the American College of Cardiology. 1990;16:533-540.  Abstract
end fo content area